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New therapies show promise in treating autoimmune diseases 




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✅   Children with autoimmune hepatitis receiving standard-of-care therapy demonstrate long-term obesity and linear growth delay

science

CONCLUSIONS: This study demonstrates that children with AIH receiving standard-of-care therapy demonstrate altered growth trajectories, long-term excess weight gain, obesity, and linear growth delay. Young age at diagnosis and >10 mg of daily prednisone at 6 months are predictors for linear growth delay. These data indicate the need to re-evaluate standard treatment algorithms for pediatric AIH in terms of steroid dosing and potential nonsteroid alternatives.

NCBI     Feb 03, 2025