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How Could a COVID Vaccine Cause Blood Clots?

science

The very rare occurrence of a mysterious blood-clotting disorder among some recipients of the Oxford–AstraZeneca COVID-19 vaccine has researchers scrambling to uncover whether and how the inoculation could trigger such an unusual reaction.
Scientific American     Apr 12, 2021

AstraZeneca COVID-19 vaccine FAQ: Why do the age recommendations keep changing? Does it cause VIPIT blood clots? Is it effective against variants?

health

The AstraZeneca vaccine was 70 per cent effective against symptomatic COVID-19 infection in a large multinational study, and recently reported 76 per cent overall efficacy against symptomatic COVID-19 in another large study done primarily in the United States. THE CANADIAN PRESS/John Woods Many people have questions about the changing guidelines for the use of AstraZeneca’s COVID-19 vaccine. Here are some answers from infectious disease specialist Dr. Alexander Wong. How is the AstraZeneca vaccine different from the other COVID-19 vaccines? ChADOx1 nCoV-19/AZD1222 (AstraZeneca’s COVID-19 vaccine, also called the Oxford-AstraZeneca vaccine and COVISHIELD) uses a modified adenovirus “vector” to deliver the genetic code for the SARS-CoV-2 spike protein to the cell nucleus. This vector has been modified so that it can enter human cells, but once inside, it cannot replicate. That means it can’t cause danger to the vaccine recipient. Once inside the cell, the DNA for the spike protein is delivered to the cell nucleus. There, the code is translated into messenger RNA (mRNA) that the cell can then use to manufacture its own spike proteins. These spike proteins then help to stimulate th...
The Conversation     Apr 11, 2021

The Guardian view on the AstraZeneca vaccine: confidence from clarity | Editorial

health

Where risk is involved, science deals in probabilities not certainties. Communication around vaccines must accept that realityEvery day, people take medicines with known side-effects. The risk is accepted when weighed against the benefit. But Covid vaccines are unfamiliar. There is no record of use over time to build public confidence. Still, they have been tested and proven to offer protection against the virus. By all usual medical standards, they are safe. That remains true for the AstraZeneca vaccine, despite an evolving picture that side-effects might include a rare blood clotting disorder.The UK’s Medicines and Healthcare Products Regulatory Authority is still investigating the link, but has recommended, as a precaution, that other vaccines be preferred for recipients under 30. That is a notable shift in policy when ministers have dismissed any talk of risks associated with the jab. The European Medicines Agency on Wednesday recommended that blood-clotting be added to the list of “very rare” side-effects of the AstraZeneca vaccine; not sufficient to require a change in patterns of use.
The Guardian     Apr 07, 2021

Khairy: Phase two of Covid-19 vaccination to kick off in eight states on Apr 19

health

A frontliner receives a dose of the Pfizer-BioNTech Covid-19 vaccine in Putrajaya, March 1, 2021. — Bernama pic Subscribe to our Telegram channel for the latest updates on news you need to know. PUTRAJAYA, April 5 — Phase two of the National Covid-19 Immunisation Programme, covering senior citizens, persons with disabilities (PwD) and those with chronic diseases, will begin on April 19 in eight states, said the programme’s Coordinating Minister Khairy Jamaluddin. googletag.cmd.push(function() { googletag.display('mm-story-outstream'); }); Phase two will kick off with Kedah, Melaka, Penang, Pahang, Sabah, Sarawak, Terengganu and the Federal Territory of Labuan, to be followed a few days later by other states according to the readiness of the vaccination centres and staff, he said. var width = (window.innerWidth > 0) ? window.innerWidth : screen.width; if(width <= 768) { googletag.cmd.push(function() { googletag.display('mm-story-320x100'); }); } Khairy said potential vaccine recipients would be notified of their appointment dates through the MySejahtera application from today. googletag.cmd.push(function() { googletag.display('mm-teads'); }); “Notifications will be sent out at least 14 days before the appointment date for receiving the vaccine, with reminders to be sent three days and one day in advance via short messaging service and call centres,” he told a joint press conference with Health Minister Datuk Seri Dr Adham Baba on the immunisation programme here today. googletag.cmd.push(function() { googletag.display('mm-story-mreg-2'); }); He said attendance is compulsory for those who have registered and pressed the button for confirmation to receive the vaccine, as thorough preparations have been made by vaccination centres and the allocated vaccines should not go to waste. — Bernama
malaymail.com     Apr 05, 2021