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How a New Blood-Vessel-on-a-Chip Can Help Researchers Further ... - UNC Health and UNC School of Medicine

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A research team led by William Polacheck, PhD, at the UNC School of Medicine, has engineered a microfluidic model that mimics a rare genetic disorder affecting the structure of veins, arteries, capillaries, and lymphatic vessels. Control cells and endothelial cells expressing PIK3CA-activating mutations cultured in 3D fibrin matrices. CHAPEL HILL, N.C. – Our bodies are made up of 60,000 miles of complex pipes that play a vital role in transporting nutrients throughout our bodies, performing waste disposal, and supplying our organs with fresh oxygen and blood. Several things can go wrong with this complex system, including vascular malformations (VMs), a group of rare genetic disorders that causes an abnormal formation of veins, arteries, capillaries, or lymphatic ...

news.unchealthcare.org     Feb 24, 2023