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✅   Ten sessions of hyperbaric oxygen versus sham treatment in patients with long covid (HOT-LoCO): a randomised, placebo-controlled, double-blind, phase II trial

Health

Objectives To evaluate if 10 sessions of hyperbaric oxygen treatments (HBOTs) improve short- and long-term health related quality of life, symptoms and physical performance in long covid patients compared with placebo. Design Parallel, randomised, placebo-controlled, double-blind trial. Setting Single-centre, university hospital, Sweden. Participants Previously healthy subjects aged 18–60 years, diagnosed with long covid were included. We excluded pregnant women, patients with RAND-36 (role limitations due to physical health (RP) and physical functioning (PF)) above 70, diabetes, hypertension and contraindications for HBOT. Interventions Subjects were randomly assigned to 10 sessions of HBOT or sham (placebo) treatments over 6 weeks.

BMJ     Apr 15, 2025