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🗞️   Impact of tiered restrictions in December 2020 on COVID-19 hospitalisations in England: a synthetic control study

Science

Objectives To evaluate the effectiveness of localised Tier 3 restrictions, implemented in England in December 2020, on reducing COVID-19 hospitalisations compared with less stringent Tier 2 measures and the variations by neighbourhood deprivation and the prevalence of Alpha (B.1.1.7) variant, the primary variant of concern then, to measure hospital services’ burden and inequalities across different communities. Design Observational study using a synthetic control method, comparing weekly hospitalisation rates in Tier 3 areas to a synthetic control from Tier 2 areas. Setting England between 4 October 2020 and 21 February 2021. Participants 23 million people under Tier 3 restrictions, compared with a synthetic control group derived from 29 million people under Tier 2 restrictions.

BMJ     Jan 06, 2025