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✅   Use of prescription opioids and other psychotropic drugs during pregnancy and their impact on the mother and developing child: protocol for a cohort study using linked administrative data from Manitoba and British Columbia, Canada

Health

Introduction Opioids are prescribed to manage pain. Approximately 1 in 20 pregnant women in Canada are prescribed opioids during the prenatal period, which may occur concurrently with other psychotropic drug use. The health implications of the independent and concurrent prenatal use of these drugs are not fully understood; however, adverse neonatal and longer-term outcomes have been suggested. This protocol describes a study to update the epidemiology of prenatal exposure to opioid and other psychotropic drug use during pregnancy, providing an enhanced understanding of the potential impacts on the mother and child to help inform decisions regarding prescription and use. Methods and analysis The retrospective cohort study design uses population-based administrative data from Manitoba and British Columbia, ...

BMJ     May 02, 2025