Environmental-factors-in-chronic-heart-disease-development  on August 24, 2024


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✅ Impact of altitude on the development of low bone mineral density and osteoporosis in individuals aged 50 years and older: protocol for a multicentre prospective cohort study

Health

Introduction Osteoporotic fractures are a leading cause of disability and contribute significantly to medical care costs worldwide. Variations in bone mineral density and the risk of osteoporosis are notably influenced by altitude. This study aims to longitudinally examine individuals with osteoporosis and low bone mass at three different altitudes (low, high and very high) to understand the effects of high-altitude environments on bone density. Methods and analysis This multicentre, prospective cohort study will involve 893 participants divided into three groups based on altitude: low (500–1500 m), high (2500–4500 m) and very high (4500–5500 m). Participants will undergo comprehensive diagnostic assessments, including demographic data collection, structured questionnaires, medical examinations and clinical laboratory tests.

BMJ     Aug 24, 2024