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SS&C GlobeOp Forward Redemption Indicator up to 3.49% in November

tech

SS&C Technologies Holdings' SS&C GlobeOp Forward Redemption Indicator, a measure of the forward redemption notices received from investors in hedge funds administered on the SS&C GlobeOp platform, measured 3.49% in November, up from from 2.29% in October.

Hedge Week     Nov 22, 2023

PAKistan Study of prEmature coronary atHerosclerosis in young AdulTs (PAK-SEHAT): a prospective longitudinal study protocol investigating the prevalence, severity and determinants of atherosclerotic cardiovascular disease in the young adult Pakistani population

Introduction Atherosclerotic cardiovascular disease (ASCVD) is a major cause of morbidity, mortality and health expenditures worldwide. Despite having higher ASCVD in the Pakistani population, data on subclinical coronary atherosclerosis in young Pakistanis remain scarce. The PAKistan Study of prEmature coronary atHerosclerosis in young AdulTs (PAK-SEHAT) aims to assess the prevalence, severity and determinants of subclinical coronary atherosclerosis among Pakistani men (35–60 years) and women (35–65 years) free of clinically symptomatic ASCVD and will assess 5-year rates of ASCVD events. Methods and analysis PAK-SEHAT is an ongoing prospective cohort study with 2000 participants from all provinces of Pakistan who will be interviewed at the baseline along with phlebotomy, measurement of carotid intima-media thickness (CIMT) and coronary CT ...

BMJ     Nov 20, 2023

Nutrients, Vol. 15, Pages 4839: Are Supplements Consumed by Middle-Distance Runners Evidence-Based? A Comparative Study between Level of Competition and Sex

Background: Middle-distance running events have special physiological requirements from a training and competition point of view. Therefore, many athletes choose to take sport supplements (SS) for different reasons. To date, few studies have been carried out that review supplementation patterns in middle-distance running. The aim of the present study is to analyze the consumption of SS in these runners with respect to their level of competition, sex and level of scientific evidence. Methods: In this descriptive cross-sectional study, data was collected from 106 middle-distance runners using a validated questionnaire. Results: Of the total sample, 85.85% responded that they consumed SS; no statistical difference was found regarding the level of competition or sex of the athletes.

mdpi.com     Nov 20, 2023

WHY STOP? A prospective observational vignette-based study to determine the cognitive-behavioural effects of rapid diagnostic PCR-based point-of-care test results on antibiotic cessation in ICU infections

Objectives Point-of-care tests (POCTs) for infection offer accurate rapid diagnostics but do not consistently improve antibiotic stewardship (ASP) of suspected ventilator-associated pneumonia. We aimed to measure the effect of a negative PCR-POCT result on intensive care unit (ICU) clinicians’ antibiotic decisions and the additional effects of patient trajectory and cognitive-behavioural factors (clinician intuition, dis/interest in POCT, risk averseness). Design Observational cohort simulation study. Setting ICU. Participants 70 ICU consultants/trainees working in UK-based teaching hospitals. Methods Clinicians saw four case vignettes describing patients who had completed a course of antibiotics for respiratory infection. Vignettes comprised clinical and biological data (ie, white cell count, C reactive protein), varied to create four trajectories: clinico-biological improvement (the ...

BMJ     Nov 21, 2023

Construction of a model for adolescent physical and mental health ... - BMC Public Health

We developed a model for promoting adolescent physical and mental health (MH) to investigate the integrated pathways of physical activity (PA), MH, general self-efficacy (GSE), and sleep duration (SD) promotion among adolescents in China. The research hypotheses were tested using questionnaires, descriptive statistics, and validated factor analysis. The mean age of the respondents was 14.94 ± 1.76 years, the PA level was 2.49 [95% confidence interval (CI): 2.46–2.53], the GSE score was 2.60 (95% CI: 2.57–2.64), the SD was 436.52 min/day (95% CI: 432.89–440.15), and the total mean MH score was 1.72 (95% CI: 1.69–1.76) (model fitness index: χ2/df = 1.295, comparative fit index = 0.999, Tucker–Lewis index = 0.997, root mean square error of approximation = 0.014, standardized root mean square residual = 0.007).

bmcpublichealth.biomedcentral.com     Nov 20, 2023